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Benzodiazepines are a class of psychoactive drugs that act as central nervous system depressants, primarily used to treat anxiety, insomnia, seizures, and muscle spasms.

Benzodiazepines work by enhancing the effect of the neurotransmitter gamma-aminobutyric acid (GABA) in the brain, which reduces neuronal excitability and produces a calming effect. They are commonly prescribed for short-term treatment of various mental health and medical conditions. However, long-term use can lead to physical dependence, tolerance, and withdrawal symptoms upon discontinuation. Benzodiazepines also have the potential for abuse and are often misused in combination with other substances.

Benzodiazepines can be detected in various types of drug tests, including urine, blood, and hair tests. The detection window varies depending on the specific drug, dosage, and individual factors such as metabolism and frequency of use. Short-acting benzodiazepines, such as alprazolam (Xanax) and lorazepam (Ativan), can be detected for 1-5 days after last use in urine tests, while long-acting benzodiazepines, such as diazepam (Valium) and clonazepam (Klonopin), can be detected for up to 30 days or longer. It is important to disclose any prescribed benzodiazepine use to employers or testing authorities to avoid false-positive results.