Trazodone
Trazodone is an antidepressant medication belonging to the class of serotonin antagonist and reuptake inhibitors (SARIs). It is primarily used to treat depression, anxiety disorders, and insomnia.
Description: Trazodone works by increasing the levels of serotonin, a neurotransmitter that plays a crucial role in regulating mood, sleep, and appetite. It does this by blocking serotonin receptors and inhibiting the reuptake of serotonin by neurons, thereby increasing its availability in the brain. Trazodone is known for its sedative properties, making it a popular choice for treating insomnia, even in non-depressed individuals.
Compared to other antidepressants, trazodone has a lower risk of causing sexual side effects and is generally well-tolerated. However, it may cause side effects such as drowsiness, dizziness, dry mouth, and blurred vision. Trazodone is not typically associated with abuse or addiction, but it can cause withdrawal symptoms if discontinued abruptly after long-term use.
Trazodone and Drug Testing: Trazodone is not commonly included in standard drug screening panels. However, if specifically tested for, it can be detected in urine for up to 4-5 days after last use, depending on factors such as dosage, frequency of use, and individual metabolism. In blood tests, trazodone can be detected for up to 24-48 hours after last use. It is essential for individuals prescribed trazodone to inform testing authorities about their medication to avoid potential false-positive results for other substances.
Examples of trazodone use:
- Treatment of major depressive disorder
- Management of anxiety disorders
- Off-label treatment for insomnia
- Adjunctive treatment for schizophrenia and other mental health conditions